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1

Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humans

Hurst, Susan, Loi, Cho-Ming, Brodfuehrer, Joanne, El-Kattan, Ayman

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2007

Language:

english

File:

PDF, 493 KB

english, 2007

2

A comprehensive review of the current evidence for trabectedin in advanced myxoid liposarcoma

Assi, Tarek, Kattan, Joseph, El Rassy, Elie, Honore, Charles, Dumont, Sarah, Mir, Olivier, Le Cesne, Axel

Journal:

Cancer Treatment Reviews

Year:

2018

Language:

english

File:

PDF, 974 KB

english, 2018

3

The effect of terpene enhancer lipophilicity on the percutaneous permeation of hydrocortisone formulated in HPMC gel systems

Ayman F El-Kattan, Charles S Asbill, Bozena B Michniak

Journal:

International Journal of Pharmaceutics

Year:

2000

Language:

english

File:

PDF, 175 KB

english, 2000

4

Encyclopedia of Reagents for Organic Synthesis || Sodium Methoxide

El-Kattan, Yahya

Year:

2001

Language:

english

File:

PDF, 252 KB

english, 2001

5

Reconciling Human-Canine Differences in Oral Bioavailability: Looking beyond the Biopharmaceutics Classification System

Martinez, Marilyn N., El-Kattan, Ayman, Awji, Elias, Papich, Mark

Journal:

The AAPS Journal

Year:

2019

Language:

english

File:

PDF, 2.08 MB

english, 2019

6

The effects of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities

Ayman F. El-Kattan, Charles S. Asbill, Nanhye Kim, Bozena B. Michniak

Journal:

International Journal of Pharmaceutics

Year:

2001

Language:

english

File:

PDF, 151 KB

english, 2001

7

The road map to oral bioavailability: an industrial perspective

Thomas, V Hayden, Bhattachar, Shobha, Hitchingham, Linda, Zocharski, Philip, Naath, Maryanne, Surendran, Narayanan, Stoner, Chad L, El-Kattan, Ayman

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2006

Language:

english

File:

PDF, 263 KB

english, 2006

8

pH-Dependent Solubility and Permeability Criteria for Provisional Biopharmaceutics Classification (BCS and BDDCS) in Early Drug Discovery

Varma, Manthena V., Gardner, Iain, Steyn, Stefanus J., Nkansah, Paul, Rotter, Charles J., Whitney-Pickett, Carrie, Zhang, Hui, Di, Li, Cram, Michael, Fenner, Katherine S., El-Kattan, Ayman F.

Journal:

Molecular Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 1.97 MB

english, 2012

9

Involvement of drug transporters in organ toxicity: the fundamental basis to drug discovery and development

Cheng, Yaofeng, El-Kattan, Ayman F, Zhang, Yan, Ray, Adrian S., Lai, Yurong

Journal:

Chemical Research in Toxicology

Year:

2016

Language:

english

File:

PDF, 1.50 MB

english, 2016

10

In utero MRI diagnosis of fetal malformations in oligohydramnios pregnancies

Said, Ahmed Hesham, El-Kattan, Eman, Abdel-Hakeem, Ahmed K., Saleem, Sahar

Journal:

The Egyptian Journal of Radiology and Nuclear Medicine

Year:

2016

Language:

english

File:

PDF, 1.10 MB

english, 2016

11

Toxicities Associated with Docetaxel-Based Regimens in the Adjuvant Treatment of Early-Stage Breast Cancer: A Multicenter Prospective Real-Life Experience

El Rassy, Elie, Ghosn, Marwan, Farhat, Fadi, Bakouny, Ziad, Assi, Tarek, Chahine, Georges, Nasr, Fadi, Haddad, Fady Ghassan, El Karak, Fadi, Kattan, Joseph

Journal:

Year:

2018

Language:

english

File:

PDF, 168 KB

english, 2018

12

Navigating Transporter Sciences in Pharmacokinetics Characterization Using Extended Clearance Classification System (ECCS)

El-Kattan, Ayman F, Varma, Manthena V S

Journal:

Drug Metabolism and Disposition

Year:

2018

Language:

english

File:

PDF, 1.96 MB

english, 2018

13

Different inhibitors for the same target in metastatic luminal breast cancer: is there any difference?

El Rassy, Elie, Bakouny, Ziad, Assi, Tarek, Kattan, Joseph

Journal:

Future Oncology

Year:

2018

Language:

english

File:

PDF, 1.31 MB

english, 2018

14

A network meta-analysis of the PD(L)-1 inhibitors in the salvage treatment of urothelial bladder cancer

Rassy, Elie El, Bakouny, Ziad, Aoun, Fouad, Haddad, Fadi G, Sleilaty, Ghassan, Assi, Tarek, Kattan, Joseph

Journal:

Year:

2018

Language:

english

File:

PDF, 751 KB

english, 2018

15

Non-small cell lung cancer brain metastases and the immune system: From brain metastases development to treatment

El Rassy, Elie, Botticella, Angela, Kattan, Joseph, Le Péchoux, Cecile, Besse, Benjamin, Hendriks, Lizza

Journal:

Cancer Treatment Reviews

Year:

2018

Language:

english

File:

PDF, 961 KB

english, 2018

16

Synergistic effects of curing conditions and magnesium oxide addition on the physico-mechanical properties and firing resistivity of Portland cement mortar

Abdel-Gawwad, H.A., Abo El-Enein, S.A., Heikal, Mohamed, Abd El-Aleem, S., Amer, A.A., El-Kattan, I.M.

Journal:

Construction and Building Materials

Year:

2018

Language:

english

File:

PDF, 6.80 MB

english, 2018

17

A comprehensive review of the role of immune checkpoint inhibitors in brain metastasis of renal cell carcinoma origin

Kattan, Joseph, Rassy, Elie El, Assi, Tarek, Bakouny, Ziad, Pavlidis, Nicholas

Journal:

Critical Reviews in Oncology/Hematology

Year:

2018

Language:

english

File:

PDF, 813 KB

english, 2018

18

Factors associated with the time to first palliative care consultation in Lebanese cancer patients

Bakouny, Ziad, Assi, Tarek, El Rassy, Elie, Daccache, Karen, Kattan, Clarisse, Tohme, Aline, Mouhawej, Marie Claire, Kattan, Joseph

Journal:

Supportive Care in Cancer

Year:

2018

Language:

english

File:

PDF, 534 KB

english, 2018

19

Effect of exogenous progesterone treatment on ovarian steroid hormones and oxidant and antioxidant biomarkers during peak and low breeding seasons in dromedary she-camel

El-Maaty, Amal M. Abo, Mohamed, Ragab H., Hozyen, Heba F., El-Kattan, Adel M., Mahmoud, Mona A., Ali, Amal H.

Journal:

Veterinary World

Year:

2019

Language:

english

File:

PDF, 663 KB

english, 2019

20

Prospective phase II trial of alternating intravesical Bacillus Calmette-Guérin (BCG) and Interferon alpha IIB in the treatment and prevention of superficial transitional cell carcinoma of the urinary bladder: Preliminary results

S. Bazarbashi, M.A. Raja, A. El Sayed, A. Ezzat, E. Ibrahim, S. Kattan, A. Kardar, A. Peracha, E. Lindstedt, K. Hanash

Journal:

Journal of Surgical Oncology

Year:

2000

Language:

english

File:

PDF, 93 KB

english, 2000

21

γ-Radiation-induced graft copolymerization of acrylic acid onto poly(ethylene terephthalate) films: A study by thermal analysis

M. Kattan, E. El-Nesr

Journal:

Journal of Applied Polymer Science

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

22

Oral treatment with PD-0200347, an α2δ ligand, reduces the development of experimental osteoarthritis by inhibiting metalloproteinases and inducible nitric oxide synthase gene expression and synthesis in cartilage chondrocytes

Christelle Boileau, Johanne Martel-Pelletier, Julie Brunet, Ginette Tardif, Denis Schrier, Craig Flory, Ayman El-Kattan, Martin Boily, Jean-Pierre Pelletier

Journal:

Arthritis & Rheumatism

Year:

2005

Language:

english

File:

PDF, 503 KB

english, 2005

23

ChemInform Abstract: A General Synthetic Method of 5-Carboranyluracil Nucleosides with Potential Antiviral Activity and Use in Neutron Capture Therapy.

N. M. GOUDGAON, Y. A. EL-KATTAN, X. XIA, J. MCATEE, J. SORIA, S.-J. WEY, D. C. LIOTTA, R. F. SCHINAZI

Journal:

Year:

1998

File:

PDF, 25 KB

1998

24

ChemInform Abstract: Tin(IV) Chloride Mediated Glycosylation in Arabinofuranose, Galactofuranose and Rhamnopyranose.

A. K. PATHAK, Y. A. EL-KATTAN, N. BANSAL, J. A. MADDRY, R. C. REYNOLDS

Journal:

Year:

1998

File:

PDF, 33 KB

1998

25

Pharmacokinetics of 5-carboranyl-2′-deoxyuridine in rats

Venkateswar R. Jarugula, Raymond F. Schinazi, Geraldine Fulcrand, Yahya El Kattan, Dennis C. Liotta, F. Douglas Boudinot

Journal:

Journal of Pharmaceutical Sciences

Year:

1994

Language:

english

File:

PDF, 408 KB

english, 1994

26

Cellular pharmacology and biological activity of 5-carboranyl-2′-deoxyuridine

Raymond F. Schinazi, Naganna M. Goudgaon, Geraldine Fulcrand, Yahya El Kattan, Zbigniew Lesnikowski, Giliyar Ullas, Joseph Moravek, Dennis C. Liotta

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1994

Language:

english

File:

PDF, 932 KB

english, 1994

27

Comparison of the anti-influenza virus activity of cyclopentane derivatives with oseltamivir and zanamivir in vivo

Pooran Chand, Shanta Bantia, Pravin L. Kotian, Yahya El-Kattan, Tsu-Hsing Lin, Yarlagadda S. Babu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 161 KB

english, 2005

28

Uranium exploration in El-Missikat prospect area, central eastern desert, Egypt

Said I. Rabie, Hassan S. Assaf, El Sayed M. El Kattan, Helmmy S. Osman

Journal:

Radiation Physics and Chemistry

Year:

1996

Language:

english

File:

PDF, 454 KB

english, 1996

29

Corrigendum to “Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores” [Bioorg. Med. Chem. 17 (2009) 3934]

Pravin L. Kotian, Raman Krishnan, Scott Rowland, Yahya El-Kattan, Surendra K. Saini, Ramanda Upshaw, Shanta Bantia, Shane Arnold, Y. Sudhakar Babu, Pooran Chand

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 94 KB

english, 2010

30

Oxadiazolone bioisosteres of pregabalin and gabapentin

David J. Wustrow, Thomas R. Belliotti, Thomas Capiris, Clare O. Kneen, Justin S. Bryans, Mark J. Field, Dic Williams, Ayman El-Kattan, Lisa Buchholz, Jack J. Kinsora, Susan M. Lotarski, Mark G. Vartan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 164 KB

english, 2009

31

Fetal MRI in the evaluation of fetuses referred for sonographically suspected neural tube defects (NTDs): impact on diagnosis and management decision

Sahar N. Saleem, Ahmed-Hesham Said, Maged Abdel-Raouf, Eman A. El-Kattan, Maha Saad Zaki, Noha Madkour, Mostafa Shokry

Journal:

Year:

2009

Language:

english

File:

PDF, 355 KB

english, 2009

32

How Modeling and Simulation Have Enhanced Decision Making in New Drug Development

Raymond Miller, Wayne Ewy, Brian W. Corrigan, Daniele Ouellet, David Hermann, Kenneth G. Kowalski, Peter Lockwood, Jeffrey R. Koup, Sean Donevan, Ayman El-Kattan, Cheryl SW Li, John L. Werth, Douglas

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2005

Language:

english

File:

PDF, 174 KB

english, 2005

33

Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores

Pravin L. Kotian, Raman Krishnan, Scott Rowland, Yahya El-Kattan, Surendra K. Saini, Ramanda Upshaw, Shanta Bantia, Shane Arnold, Y. Sudhakar Babu, Pooran Chand

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.30 MB

english, 2009

34

Tin(IV) chloride mediated glycosylation in arabinofuranose, galactofuranose and rhamnopyranose

Ashish K. Pathak, Yahya A. El-Kattan, Namita Bansal, Joseph A. Maddry, Robert C. Reynolds

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 198 KB

english, 1998

35

ChemInform Abstract: Nitrogen Glycosylation Reactions Involving Pyrimidine and Purine Nucleoside Bases with Furanoside Sugars

L. J. WILSON, M. W. HAGER, Y. A. EL-KATTAN, D. C. LIOTTA

Journal:

Year:

1996

File:

PDF, 25 KB

1996

36

OP05.02: 3D multislice analysis of ultrasound volumes for the prenatal diagnosis of central nervous system fetal malformations

M. Momtaz, A. Ebrashy, M. Aboulghar, I. El-Kattan, M. Sherif, A. Hamed

Journal:

Ultrasound in Obstetrics & Gynecology

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

37

Survey of utilization of multidisciplinary management tumor boards in Arab countries

Nagi S. El Saghir, Nadine El-Asmar, Carla Hajj, Toufic Eid, Sami Khatib, Adda Bounedjar, Dahish Ajarim, Ali Shamseddine, Fady Geara, Abdelrahman Jazieh, Hamdy A. Azim, Yasser Abdelkader, Joseph Kattan

Journal:

Year:

2011

Language:

english

File:

PDF, 135 KB

english, 2011

38

Evaluation of derivatives of 3-(2-oxo-1-pyrrolidine) hexahydro-1H-azepine-2-one as dermal penetration enhancers: side chain length variation and molecular modeling

N Kim, A.F El-Kattan, C.S Asbill, R.J Kennette, J.W Sowell Sr., R Latour, B.B Michniak

Journal:

Journal of Controlled Release

Year:

2001

Language:

english

File:

PDF, 499 KB

english, 2001

39

Transdermal testing: practical aspects and methods

El-Kattan, Ayman, Asbill, Charles S, Haidar, Sam

Journal:

Pharmaceutical Science & Technology Today

Year:

2000

Language:

english

File:

PDF, 174 KB

english, 2000

40

Full efficacy with no CNS side-effects: unachievable panacea or reality? DMPK considerations in design of drugs with limited brain penetration

Cole, Susan, Bagal, Sharan, El-Kattan, Ayman, Fenner, Katherine, Hay, Tanya, Kempshall, Sarah, Lunn, Graham, Varma, Manthena, Stupple, Paul, Speed, William

Journal:

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

41

Uterine–umbilical artery Doppler velocimetry and pregnancy outcome in SLE patients: Relation to disease manifestations and activity

Tamer A. Gheita, Sherif M. Gamal, Eman El-Kattan

Journal:

The Egyptian Rheumatologist

Year:

2011

Language:

english

File:

PDF, 684 KB

english, 2011

42

Modulation of NMDA receptor function by inhibition of d-amino acid oxidase in rodent brain

Christine A. Strick, Cheryl Li, Liam Scott, Brian Harvey, Mihály Hajós, Stefanus J. Steyn, Mary A. Piotrowski, Larry C. James, James T. Downs, Brian Rago, Stacey L. Becker, Ayman El-Kattan, Youfen Xu,

Journal:

Neuropharmacology

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011

43

Comparative pharmacokinetics of marbofloxacin in healthy and Mannheimia haemolytica infected calves

M. Ismail, Y.A. El-Kattan

Journal:

Research in Veterinary Science

Year:

2007

Language:

english

File:

PDF, 156 KB

english, 2007

44

Unusual presentation of rib exostosis

Waseem M Hajjar, Yasser M El-Medany, Mohamed A Essa, Mohamad A Rafay, Mahmoud H Ashour, Khaled M Al-Kattan

Journal:

The Annals of Thoracic Surgery

Year:

2003

Language:

english

File:

PDF, 154 KB

english, 2003

45

A Practical Large-Scale Synthesis of (3 R ,4 R )-4-(Hydroxymethyl)pyrrolidin-3-ol via Asymmetric 1,3-Dipolar Cycloaddition

Kotian, Pravin L., Lin, Tsu-Hsing, El-Kattan, Yahya, Chand, Pooran

Journal:

Organic Process Research & Development

Year:

2005

Language:

english

File:

PDF, 59 KB

english, 2005

46

Characterization of Organic Anion Transporting Polypeptide (OATP) Expression and Its Functional Contribution to the Uptake of Substrates in Human Hepatocytes

Kimoto, Emi, Yoshida, Kenta, Balogh, Larissa M., Bi, Yi-an, Maeda, Kazuya, El-Kattan, Ayman, Sugiyama, Yuichi, Lai, Yurong

Journal:

Molecular Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

47

Physicochemical Determinants of Human Renal Clearance

Varma, Manthena V. S., Feng, Bo, Obach, R. Scott, Troutman, Matthew D., Chupka, Jonathan, Miller, Howard R., El-Kattan, Ayman

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

48

Physicochemical Space for Optimum Oral Bioavailability: Contribution of Human Intestinal Absorption and First-Pass Elimination

Varma, Manthena V. S., Obach, R. Scott, Rotter, Charles, Miller, Howard R., Chang, George, Steyn, Stefanus J., El-Kattan, Ayman, Troutman, Matthew D.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

49

Model-based approaches to predict drug–drug interactions associated with hepatic uptake transporters: preclinical, clinical and beyond

Barton, Hugh A, Lai, Yurong, Goosen, Theunis C, Jones, Hannah M, El-Kattan, Ayman F, Gosset, James R, Lin, Jian, Varma, Manthena V

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2013

Language:

english

File:

PDF, 671 KB

english, 2013

50

Diethylation Labeling Combined with UPLC/MS/MS for Simultaneous Determination of a Panel of Monoamine Neurotransmitters in Rat Prefrontal Cortex Microdialysates

Ji, Chengjie, Li, Wenlin, Ren, Xiao-dan, El-Kattan, Ayman F., Kozak, Rouba, Fountain, Scott, Lepsy, Christopher

Journal:

Analytical Chemistry

Year:

2008

Language:

english

File:

PDF, 266 KB

english, 2008

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